Unscramble HISTOLYSIS and you have 169 words, HISTOLYSIS itself among them: it scores 16 in Scrabble and 15 in Words With Friends. 10 letters: 3 vowels and 7 consonants.
H43I1S1T1O1L12Y43S1I1S1
Scrabble value on each tile, blue for Words With Friends when different.
By length, the words from HISTOLYSIS split into 1 with 10 letters, 2 with 8, 6 with 7, 13 with 6, 40 with 5, 54 with 4, 35 with 3 and 18 with 2. None has 9 letters.
4 of 40 5-letter words from HISTOLYSIS tie at 11 points; none scores more. LISTS, SHOTS and SLOTS will look familiar.
HOLY and HOYS share the top score of 10 among the 4-letter words made with HISTOLYSIS letters. LIST, TOYS and LOSS are the ones most people know.
Keep every letter of HISTOLYSIS but one, change that one, and you get:
More 10-letter words: starting with HI · ending in IS · all 10-letter words
Short meanings for the 7 highest-scoring answers, starting with STYLISH (13 points).
Score: Scrabble · Words With Friends
HISTOLYSIS works in Scrabble US and Scrabble UK, and it appears in the list Words With Friends is built on.
| Game | Scrabble US | Scrabble UK | Words With Friends* |
|---|---|---|---|
| HISTOLYSIS itself | Yes | Yes | Yes |
| Answers accepted (of 169) | 129 | 169 | 123 |
* Based on the list Words With Friends started from; the live game may differ.
40 of the 169 answers are missing from Scrabble US and Words With Friends*: HYLOISTS, THYLOSIS, HYLISTS, HYLOIST, HYLIST, SLYISH, TOSHY, TOSSILY, TYLOSIS, SHISOS, STYLOS, HIOIS and 28 more. 6 of the 169 answers are missing from Words With Friends*: HOSS, SOHS, HOS, SHO, SOH and OI.